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Douglas McDonald, MD, MS

Douglas McDonald, MD, MS

Professor, Orthopaedic Surgery

Division of Musculoskeletal Oncology

Chief, Musculoskeletal Oncology

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(314) 514-3500

Dr. McDonald is Professor of Orthopaedic Surgery at Washington University School of Medicine. He is board certified and a nationally recognized orthopaedic surgeon specializing in musculoskeletal oncology and adult reconstructive surgery of the hip and knee. Dr. McDonald received his medical degree from the University of Minnesota in 1982 and Master of Science degree from the University of Minnesota in 1987. He completed his orthopaedic surgery at the Mayo Graduate School of Medicine in 1987. He completed a Fellowship in orthopaedic oncology at the Mayo Clinic and an additional Fellowship in orthopaedic oncology at the Rizzoli Orthopaedic Institute in Bologna, Italy. Dr. McDonald’s primary expertise lies in the treatment of benign and malignant bone and soft tissue tumors of the extremities in children and adults. His hip and knee reconstructive surgery practice focuses on routine and complex joint replacement surgery.

Common Diagnoses Treated

  • All soft tissue sarcomas
  • Benign cartilage tumor of bone
  • Chondrosarcoma
  • Degenerative arthritis of the hip and knee
  • Ewing sarcoma
  • Failed total joint arthroplasty of the hip and knee
  • Giant cell tumor of bone
  • Osteosarcoma

Common Procedures

  • Biopsy of bone and soft tissue tumors
  • Endoprosthetic reconstruction following limb sparing resections
  • Excision and curettage of benign bone tumors
  • Large fragment allograft reconstruction following limb sparing resections
  • Limb sparing resection
  • Malignant bone and soft tissue tumors
  • Total hip and revision total hip arthroplasty
  • Total knee and revision total knee arthroplasty

Clinical Office Locations

  • Center for Advanced Medicine (CAM)

    Barnes Jewish Hospital

    4921 Parkview Place

    St Louis, MO 63110

Hospital Affiliations

  • Barnes-Jewish Hospital
  • Shriners Hospital for Children
  • St. Louis Children's Hospital

Academic Office Mailing Address

  • Washington University School of Medicine

    Campus Box 8233

    660 Euclid Avenue

    Saint Louis, MO 63110

  • Sim FH, McDonald DJ: The Hauser procedure revisited. Orthopedic Review 1985; 3:45-50. McDonald DJ, Sim FH, McLeod RA, Dahlin DC: Giant cell tumor of bone. J Bone Joint Surg 1986; 68A:235-242. 
  • Sim FH, Wold LE, Beabout JW, Amadio PL, McDonald DJ: Osteosarcoma: State of the art. Minn Med 1986; 69(8):442-448. Lackman RD, McDonald DJ, Beckenbaugh RD, Sim FH: Fibular reconstruction for giant cell tumor of the distal radius. Clin Orthop 1987; 218:232-238. 
  • McDonald DJ, Sim FH: Total hip arthroplasty in Paget’s disease. J Bone Joint Surg 1987; 69A:766-772. McDonald DJ, Fitzgerald RH Jr, Chao EY: The enhancement of fixation of a porous-coated femoral component by autograft and allograft in the dog. J Bone Joint Surg 1988; 70A: 728-737. 
  • Avella M, Bacci G, McDonald DJ, DiScioscio M, Picci P, Campanacci M: Adjuvant chemotherapy with six drugs (Adriamycin, Methotrexate, Cisplatinum, Bleomicyn, Cyclophosphamide, and Dactinomycin) for non metastatic high grade osteosarcoma of the extremities. Chemioterapia 1988; 7(2):133-137. 
  • Bacci G, Avella M, McDonald DJ, Toni A, Orlandi M, Campanacci M: Serum lactate dehydrogenase (LDH) as a tumor marker in Ewing’s sarcoma. Tumouri 1988; 74:649-655. 
  • Baran GA, McDonald DJ, Sundaram M: Monostotic Paget’s disease of the sacrum. Orthopedics 1989; 12(5):750-756. McDonald DJ, Fitzgerald RH Jr: The two-stage reconstruction of the infected total hip arthroplasty. J Bone Joint Surg 1989; 71A:828-834. 
  • Sundaram M, McDonald DJ, Merenda G: Intramuscular myxoma – a rare but important association with fibrous dysplasia of bone. Am J. Roentgenology 1989; 1(4):107-108. 
  • Sundaram M, McDonald DJ: The role of magnetic resonance imaging in the evaluation of the solitary tumor or tumor-like lesion of bone. Top Magn Reson Imag 1989; 1(4):17-29. 
  • Bacci G, Dallari D, McDonald DJ, Avella M, Toni A, Barbieri E, Ciaroni D, Sudanese A, Picci P, Campanacci M: Neoadjuvant chemotherapy for localized Ewing’s sarcoma of the extremities: Preliminary results of a protocol which uses surgery (alone or followed by radiotherapy) for local control. Tumouri 1989; 75:456-462. 
  • Mignani G, McDonald DJ, Boriana S, Avella M, Gaiani L, Campanacci M: Soft tissue metastasis from carcinoma: A case report and review of the literature. Tumouri 1989; 75(6):630-633. 
  • McDonald DJ, Capanna R, Gherlinzoni F, Campanacci M: Complications of limb-salvage surgery of the extremities. Cancer 1990; 65(7):1509-1516. 
  • Capanna R, Toni A, Sudanese A, McDonald DJ, Bacci G, Campanacci M: Ewing’s sarcoma of the pelvis. Intern Orthop 1990; 14(1):57-61. 
  • Sundaram M, Baran G, Merenda G, McDonald DJ: Myxoid liposarcoma: MR appearances with clinical and histological correlation. Skeletal Radiol 1990; 19(5): 359-362. 
  • Sundaram M and McDonald DJ: Magnetic resonance imaging in the evaluation of the solitary tumor of bone. Current Opinion Radiol 1990; 2:697-702. 
  • Bilotta W, Walker H, McDonald DJ, Sundaram M: Thrombosed leaking popliteal aneurysm. Skeletal Radiol 1991; 20:71-72. 20. 
  • Capanna R, Ruggieri P, Biagini R, Ferraro A, DeCristofaro R, McDonald DJ, Campanacci M: The effect of quadriceps excision on functional results following distal femur resection and prosthetic replacement for bone tumors. Clin Orthop 1991; 267:186-196. 
  • Kaufman GA, Sundaram M, McDonald DJ: MR imaging in symptomatic Paget’s disease. Skeletal Radiol 1991; 20:413-418. 
  • Schajowicz F, Granato DB, McDonald DJ, Sundaram M: Clinical and radiological features of atypical giant cell tumors of bone. Brit J Radiol 1991; 64:877-889. 
  • Martin D, McDonald DJ, Merenda G, Sundaram M: Recurrent hemarthrosis associated with gout. Clin Orthop 1992; 277:262-265. 
  • McDonald DJ, Schajowicz F: Giant cell tumor of the capitate. Clin Orthop 1992; 279:264-268. 
  • Sundaram M, Percelay S, McDonald DJ, Janney C: Extraskeletal chondrosarcoma. Skeletal Radiol 1993; 22:449-451. 
  • Shapeero LG, Vanel D, Sundaram J, Ackerman LV, Wuisman P, Bauer TW, Neuenschwander S, Contesso G, Janney C, McDonald DJ, Genin J: Periosteal Ewing sarcoma. Radiol 1994; 191:825-831. 
  • McDonald DJ: Limb-salvage surgery for treatment of sarcomas of the extremities. Am J Roentgenology 1994; 163:509-513. 
  • Clohisy JC, Schajowicz F, Vaziri DM, McDonald DJ, Connolly TJ, Sotelo-Avila C, and Betts JE: Assessment of argyrophilic nucleolar organizer region quantification in benign and malignant bone tumors. Clin Orthop 1995; 310:229-236. 
  • Sharafuddin MJA, Sundaram M, McDonald DJ: Progression from simple joint effusion to extensive pigmented villonodular synovitis of the hip within 2 years: Demonstration with MR imaging. Am J Roentgenology 1995; 165:742. 
  • Igoo D, Sundaram M, McDonald DJ, Janney C, Chalk DE. Appendicular metastatic prostate cancer simulating osteosarcoma, Paget’s disease, and Paget’s sarcoma. Skeletal Radiol 1995; 24:447-449. 
  • Sundaram M, McDonald DJ, Engel E, Rotman M, and Siegfried EC: Chronic recurrent multifocal osteomyelitis: An evolving clinical and radiological spectrum. Skeletal Radiol 1996; 25:333-336. 
  • Wright T, Sundaram M, McDonald DJ: Radiologic case study. Tuberculous osteomyelitis and arthritis. Orthopedics 1996; 19(8):699-702. 
  • Sundaram M, Falbo S, McDonald DJ, Janney C. Surface osteomas of the appendicular skeleton. Am J Roentgenology 1996; 165:742. 
  • Glenski WJ, McDonald DJ, and Sundaram M: Giant cell tumor of bone: Pattern of soft-tissue recurrence. Electronic AJR 1997; 2:11. 
  • Sundaram M, McDonald DJ, Steigman C, and Bocchini T: Metachronous multiple aneurysmal bone cysts. Skeletal Radiology 1997; 26:564-567. 
  • Akduman E, Sundaram M, McDonald DJ: SAPHO Electronic AJR 6:17: http://www.arrs.org/eajr/caseofweek, Dec 1998. 
  • Sundaram M, Akduman E, White L, McDonald DJ, Kandel R, Janney C: Primary leiomyosarcoma of bone. Am J Roentgenology 1999; 172:771-776. 
  • Sundaram M, Janney C, McDonald DJ. Myxoma of the humerus: an exceptional site of origin. Skeletal Radiology 2000; 29:57-60. 
  • Glockner J, White L, Sundaram M, McDonald DJ, : Unsuspected metastases presenting as solitary soft tissue lesions: A fourteen year review. Skeletal Radiology 2000; 29:270-274. 
  • McDonald DJ, Scott S, Eckardt JJ. Tibial turn-up for long distal femoral bone loss. Clin Orthop 2001; 383: 214-220. 
  • Sundaram M, Totty W, Kryiakos M, McDonald DJ, Merkel K. Image findings in Pseudocystic osteosarcoma. Am J Roentgenology 2001; 176 (3): 738. 
  • Sundaram M, McDonald DJ. The (y)ear of the rabbit. Am J Roentgenology 2001; 176 (3): 750. 
  • Robinson P, White LM, Sundaram M, Kandel R, Wunder J, McDonald DJ, Janney C, Bell RS. Periosteal chondroid tumors: radiologic evaluation with pathologic correlation. Am J Roentgenology 2001; 177(5): 1183-1188. 
  • McDonald DJ, Enneking WF, Sundaram M. Metal associated angiosarcoma of bone. Clin Orthop 2002; 396: 206-214. 
  • Kyriakos M, McDonald DJ, Sundarum M. Fibrous Dysplasia with Cartilaginous Differentiation (“fibrocartilaginous dysplasia”): A review with an illustrative case followed for 18 Years. Skeletal Radiology 2004, 33:51-62. 
  • Clohisy JC, Calvert G, Tull F, McDonald DJ, Maloney WJ. Reasons for revision hip surgery. Clin Orthop 2004; 429: 188-192. 
  • Ramo BA, Kyriakos M, McDonald DJ. Osteosarcoma presenting without roentgenographic evidence of tumor. Clin Orthop 2006; 442: 267-272. 
  • Patel AA, Ricci WM, McDonald DJ, Borrelli J, Clohisy JC. Treatment of periprosthetic femoral shaft non-union. J of Arthroplasty 2006; 21(3): 435-442. 
  • Posligua L, McDonald DJ, Dehner LP. Localized tenosynovial (diffuse-type) giant cell tumor in association with neurofibromatosis Type I Noonan syndrome: possibly more than a chance relationship. Am J Surg Path 2006; 30(6): 734-738. 
  • Kyriakos M, El-Khoury GY, McDonald DJ, Buckwalter JA, Sundaram M, DeYoung B, and O’Brien MP. Osteoblastomatosis of bone. A benign, multifocal osteoblastic lesion, distinct from osteoid osteoma and osteoblastoma, radiologically simulating a vascular tumor. Skeletal Radiology 2007; 36: 237-247. 
  • Burnett RSJ, Clohisy JC, McDonald DJ, Wright RW, Shively RA, Givens SA, Barrack RL. Failure of the American College of Chest Physicians 1A Protocol for Lovenox in Clinical Outcomes for Thromboembolic Prophylaxis. Journal of Arthroplasty 2007; 22(3): 317-24. 
  • Pingsterhaus JM, Peelle MW, Sicard GA, McDonald DJ. Pseudoaneurysm from traumatic osteochondroma leading to rapid neurological compromise. Orthopedics 2007; 30(5): 399-400. 
  • Basu D, Siegel BA, McDonald DJ, Nussenbaum B. Detection of Occult Bone Metastases from Head and Neck Squamous Cell Carcinoma: Impact of PET/CT Imaging. Arch Otolaryngol Head Neck Surg 2007; 133(8): 801-5. 
  • Ito H, Maloney CM, Crowninshield RD, Clohisy JC, McDonald DJ, Maloney WJ. In vivo femoral head damage and its effect on polyethylene wear. J Arthroplasty 2010; 25(2):302-8. 
  • Ramo BA, Griffin AM, Gill CS, Schwartz HS, Holt GE, McDonald DJ, Wunder JS, and Phillips SE. Incidence of Symptomatic Venous Thromboembolism in Lower Extremity Oncologic Endoprostheses. J. Bone Joint Surgery 2011; 93(9):847-54. 
  • Nassif N, Buchowski J, Osterman K, McDonald DJ. Surgical technique: iliosacral reconstruction with minimal spinal instrumentation. Clin Orthop 2013; 471(3):947-55. 
  • Friedman MV, Kyriakos M, Matava MJ, McDonald DJ, Jennings JW, Wessell DE. Intra-articular synovial sarcoma. Skeletal Radiology 2013; 42(6):859-67. 
  • McDonald DJ. Perspective on hydroxyapatite-coated collars for bone-bridging: commentary on an article by Melanie Jean Coathup, BSc(Hon), PhD, et al.: “Long term survival of cemented distal femoral endoprostheses with a hydroxyapatite-coated collar. A histological study and a radiographic follow-up”. JBone Joint Surg Am. 2013; 95(17):e1281-2. 
  • Barrack RL, Krempec JA, Clohisy JC, McDonald DJ, Ricci WM, Ruh EL, Nunley RM. Accuracy of acetabular component position in hip arthroplasty. JBone Joint Surg Am. 2013; 95(19):1760-8. 
  • Demertzis J, Kyriakos M, Loomans R, McDonald DJ, Wessell DE. Synovial hemangioma of the hip joint in a pediatric patient. Skeletal Radiology. In press.

Research Interests

Limb salvage techniques for the management of malignant bone and soft tissue tumors; Pathology of bone tumors

Clinical Interests

The management of bone and soft tissue tumors of the musculoskeletal system in both adults and children; Primary and revision total hip and total knee arthroplasty

Background

Dr. McDonald is Professor of Orthopaedic Surgery at Washington University School of Medicine. He is board certified and a nationally recognized orthopaedic surgeon specializing in musculoskeletal oncology and adult reconstructive surgery of the hip and knee. Dr. McDonald received his medical degree from the University of Minnesota in 1982 and Master of Science degree from the University of Minnesota in 1987. He completed his orthopaedic surgery at the Mayo Graduate School of Medicine in 1987. He completed a Fellowship in orthopaedic oncology at the Mayo Clinic and an additional Fellowship in orthopaedic oncology at the Rizzoli Orthopaedic Institute in Bologna, Italy. Dr. McDonald’s primary expertise lies in the treatment of benign and malignant bone and soft tissue tumors of the extremities in children and adults. His hip and knee reconstructive surgery practice focuses on routine and complex joint replacement surgery.

Board Certifications

  • American Board of Orthopaedic Surgery, 1990; Recertified, 2001

Medical Degree

  • University of Minnesota Medical School - Twin Cities

Residency

  • Orthopaedic Surgery, Mayo Clinic / Mayo Graduate School of Medicine

Fellowship

  • Orthopaedic Oncology, Instituto Ortopedico Rizzoli
  • Orthopaedic Oncology, Mayo Graduate School of Medicine

Honors and Awards:

  • AOA; Hatcher Pathology Fellow; Best Doctors in America® 2009-Present
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Dr. McDonald’s Office Locations

Center for Advanced Medicine (CAM)

Barnes Jewish Hospital

4921 Parkview Place

St Louis, MO 63110

Disclaimer

The Department of Orthopaedic Surgery at Washington University School of Medicine in St. Louis has no control over third-party websites and does not review such websites. The university disclaims any responsibility for the content of third-party websites and the use of any information on these sites.